{"id":1332,"date":"2022-05-16T08:34:39","date_gmt":"2022-05-16T08:34:39","guid":{"rendered":"https:\/\/www.aquacombine.eu\/?page_id=1332"},"modified":"2022-05-16T08:36:30","modified_gmt":"2022-05-16T08:36:30","slug":"anti-inflammatory-and-regenerative-effects-of-halophyte-bioactive-extracts-on-common-skin-diseases","status":"publish","type":"page","link":"https:\/\/www.aquacombine.eu\/?page_id=1332","title":{"rendered":"Anti-inflammatory and regenerative effects of Halophyte Bioactive Extracts on common skin diseases"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1332\" class=\"elementor elementor-1332\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c985cb4 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"c985cb4\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5fdb93d\" data-id=\"5fdb93d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-17b0af0 elementor-widget elementor-widget-heading\" data-id=\"17b0af0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Anti-inflammatory and regenerative effects of Halophyte Bioactive Extracts on common skin diseases<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bfdc449 elementor-widget elementor-widget-text-editor\" data-id=\"bfdc449\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>First data indicates an overall effect of the bioactive cream to reduce histamine induced itch.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-83ae14d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"83ae14d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e6c727b\" data-id=\"e6c727b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-16552ce elementor-widget elementor-widget-text-editor\" data-id=\"16552ce\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Halophyte plants are salt-tolerant and are acclimated for growth in saline soils such as along coastal areas. Among the halophytes the Salicornia species have been used as both folk medicine and functional feed for multiple years due to high levels of bioactive compounds including anti-inflammatory and antioxidative effects. Halophyte farming in synergy with aquaculture may be used to create high value-added products in the cosmetic and pharmaceutical industry through the implements of continual use of resources and waste through prevention, reduction, and recycling. The properties of Salicornia bioactive extracts, for modulation of pain and itch sensation, remain still unclear. Prior to clinical assessment of such salicornia extract on skin conditions the effect of the prolonged application of aqueous extracts have to be addressed using healthy subjects. In an exploratory study we obtained ethical approval to test 30 healthy volunteers for treatment with 10% Salicornia cream or inert vehicle cream for 24 or 48 hours. On day 0, and 24 or 48 hours post cream application thermal detection and pain thresholds, mechanical pain thresholds and sensitivity, and micro-vascular reactivity were assessed to evaluate the effects of cream containing Salicornia. Our data indicate an overall effect of the bioactive cream to reduce histamine induced itch although the study design and time-frame selected also show need for further assessment of the long-term effect after prolonged use. Future use of green technologies and renewable ingredients, as the S. ramosissima infused skin cream, as a putative primary treatment to reduce symptoms like itch and pain in different skin diseases, such as psoriasis and atopic dermatitis, could be favorable. Reference: 10.3390\/ph15020150\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0bf335e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0bf335e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e0a8ac0\" data-id=\"e0a8ac0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-52ac3b7 elementor-widget elementor-widget-image\" data-id=\"52ac3b7\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"2240\" height=\"1021\" src=\"https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2.png\" class=\"attachment-full size-full wp-image-1305\" alt=\"\" srcset=\"https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2.png 2240w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2-300x137.png 300w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2-1024x467.png 1024w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2-768x350.png 768w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2-1536x700.png 1536w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2-2048x933.png 2048w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2-685x312.png 685w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2-2000x912.png 2000w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2-24x11.png 24w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2-36x16.png 36w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/22-05-04_pic_Allan_2-48x22.png 48w\" sizes=\"(max-width: 2240px) 100vw, 2240px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Laboratory sample preparation for testing of plant extracts \u2013 general situation Rocco Giordano<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e5fdb9b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e5fdb9b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5cb8e6f\" data-id=\"5cb8e6f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dffc56c elementor-widget elementor-widget-text-editor\" data-id=\"dffc56c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Contact:<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3361158 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3361158\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-a7ebbf0\" data-id=\"a7ebbf0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4cd7404 elementor-widget elementor-widget-image\" data-id=\"4cd7404\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1024\" height=\"319\" src=\"https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/Bactericidal_contact_Im-1024x319.png\" class=\"attachment-large size-large wp-image-1330\" alt=\"\" srcset=\"https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/Bactericidal_contact_Im-1024x319.png 1024w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/Bactericidal_contact_Im-300x94.png 300w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/Bactericidal_contact_Im-768x239.png 768w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/Bactericidal_contact_Im-685x214.png 685w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/Bactericidal_contact_Im-24x7.png 24w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/Bactericidal_contact_Im-36x11.png 36w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/Bactericidal_contact_Im-48x15.png 48w, https:\/\/www.aquacombine.eu\/wp-content\/uploads\/2022\/05\/Bactericidal_contact_Im.png 1039w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-c2215b3\" data-id=\"c2215b3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c8e4791 elementor-widget elementor-widget-text-editor\" data-id=\"c8e4791\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Allan Stensballe, Thomas Poulsen &amp; Rocco Giordano <br \/>Aalborg University, Denmark<br \/><a href=\"mailto:as@hst.aau.dk\">as@hst.aau.dk<\/a>, tbgp@hst.aau.dk &amp; rg@hst.aau.dk<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Anti-inflammatory and regenerative effects of Halophyte Bioactive Extracts on common skin diseases First data indicates an overall effect of the bioactive cream to reduce histamine induced itch. Halophyte plants are salt-tolerant and are acclimated for growth in saline soils such as along coastal areas. Among the halophytes the Salicornia species have been used as both &hellip; <a href=\"https:\/\/www.aquacombine.eu\/?page_id=1332\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Anti-inflammatory and regenerative effects of Halophyte Bioactive Extracts on common skin diseases<\/span><\/a><\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-1332","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.aquacombine.eu\/index.php?rest_route=\/wp\/v2\/pages\/1332","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.aquacombine.eu\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.aquacombine.eu\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.aquacombine.eu\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.aquacombine.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1332"}],"version-history":[{"count":3,"href":"https:\/\/www.aquacombine.eu\/index.php?rest_route=\/wp\/v2\/pages\/1332\/revisions"}],"predecessor-version":[{"id":1335,"href":"https:\/\/www.aquacombine.eu\/index.php?rest_route=\/wp\/v2\/pages\/1332\/revisions\/1335"}],"wp:attachment":[{"href":"https:\/\/www.aquacombine.eu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1332"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}